Clinzem - Gel is an effective combination of Clindamycin & Nicotinamide in the Gel form. It's used in tropical treamement of inflammatory and Severe Acne Valgaris. This medication is used to treat acne. It helps to decrease the number of acne lesions. Clindamycin is an antibiotic which works by stopping the growth of bacteria. How to use Clindamycin Phosphate Gel Use this medication only on the skin. Clean and dry the affected area first. Follow all directions on the product package, or use as directed by your doctor. If you are using the lotion, shake the bottle well before using. Apply a thin layer of medication usually twice a day or as directed by your doctor.